Gene Information
Gene NameUNQ720/PRO1385
OrganismHomo sapiens (Human)
Gene Length369
Protein NamesProtein RIC-3 (Resistant to inhibitor of cholinesterase 3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ7Z5B4
Gene CardRIC3
Uniprot IDQ7Z5B4
PfamPF15361
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityBroadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland. Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:17640815, ECO:0000269|PubMed:18691158}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17855498  rs55990541 
Subcellular location [CC][Isoform 1]: Endoplasmic reticulum membrane;
Single-pass membrane protein.;
[Isoform 2]: Endoplasmic reticulum membrane;
Single-pass membrane protein. Golgi apparatus membrane;
Single-pass membrane protein.
Mouse PG classificationNA
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