| Gene Information | |
|---|---|
| Gene Name | SLC23A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 598 |
| Protein Names | Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) |
| Target Name | solute carrier family 23 member 1 |
| Target Type | Successful target |
| Gene Age | 1488 ( ENSG00000170482 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9UHI7 |
| Gene Card | SLC23A1 |
| Uniprot ID | Q9UHI7 |
| Pfam | PF00860 |
| In ASD | no |
| Allosteric Prediction | no (-0.132816848) |
| Ortholog in Animals | Alpaca_ SLC23A1 ( ortholog_one2one ) Dog_ SLC23A1 ( ortholog_one2one ) GuineaPig_ SLC23A1 ( ortholog_one2one ) Macaque_ SLC23A1 ( ortholog_one2one ) Mouse_ Slc23a1 ( ortholog_one2one ) Pig_ SLC23A1 ( ortholog_one2one ) Rat_ Slc23a1 ( ortholog_one2one ) Rabbit_ SLC23A1 ( ortholog_one2one ) |
| Ohnologs | SLC23A2 |
| Paralogs | SLC23A2, SLC23A3 |
| Tissue | duodenum, kidney, small.intestine, oviduct, liver, small.intestine.Peyers.patch |
| Tissue Specificity | Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. {ECO:0000269|PubMed:10556483}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs34521685 rs35817838 rs33972313 rs6596474 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10631088, ECO:0000269|PubMed:19379732}; Multi-pass membrane protein {ECO:0000269|PubMed:19379732}. |
| Mouse PG classification | NA |
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