Gene Information
Gene NameUNQ6507/PRO23203
OrganismHomo sapiens (Human)
Gene Length490
Protein NamesMetalloreductase STEAP2 (EC 1.16.1.-) (Prostate cancer-associated protein 1) (Protein up-regulated in metastatic prostate cancer) (PUMPCn) (Six-transmembrane epithelial antigen of prostate 2) (SixTransMembrane protein of prostate 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8NFT2
Gene CardSTEAP2
Uniprot IDQ8NFT2
PfamPF03807; PF01794
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary. {ECO:0000269|PubMed:12095985, ECO:0000269|PubMed:12429817, ECO:0000269|PubMed:16609065}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs194520  rs17863046  rs13228098  rs194524  rs194525 
Subcellular location [CC]Endosome membrane {ECO:0000250};
Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:12429817};
Multi-pass membrane protein {ECO:0000269|PubMed:12429817}.
Mouse PG classificationNA
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