| Gene Information | |
|---|---|
| Gene Name | UNQ6453/PRO34004 |
| Organism | Homo sapiens (Human) |
| Gene Length | 553 |
| Protein Names | Solute carrier family 22 member 12 (Organic anion transporter 4-like protein) (Renal-specific transporter) (RST) (Urate anion exchanger 1) (URAT1) (Urate:anion antiporter SLC22A12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96S37 |
| Gene Card | SLC22A12 |
| Uniprot ID | Q96S37 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in kidney (at protein level). Detected in fetal and adult kidney. Detected in epithelial cells of proximal tubules in renal cortex. {ECO:0000269|PubMed:12024214, ECO:0000269|PubMed:15304510}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12800450 rs141570522 rs121907896 rs144328876 rs149722479 rs201181059 rs121907893 rs145738825 rs121907894 rs374858585 rs1047976958 rs765990518 rs146388519 rs121907895 rs2039413303 rs145200251 rs147647315 rs773677616 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:12024214, ECO:0000269|PubMed:22194875, ECO:0000269|PubMed:35144162, ECO:0000269|PubMed:35462902}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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