| Gene Information | |
|---|---|
| Gene Name | KIAA1244 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2177 |
| Protein Names | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q5TH69 |
| Gene Card | ARFGEF3 |
| Uniprot ID | Q5TH69 |
| Pfam | PF20252; PF16213; PF09324 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in breast cancer cell lines. Not expressed in normal tissues such as duct, mammary gland, lung, heart, liver, kidnay, bone marrow. {ECO:0000269|PubMed:19496786}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9376338 rs7764091 rs3736706 rs35964895 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19496786}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q3UGY8}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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