| Gene Information | |
|---|---|
| Gene Name | TSSK1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 367 |
| Protein Names | Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A) |
| Target Name | testis-specific serine/threonine-protein kinase 1 |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000212122 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BXA7 |
| Gene Card | TSSK1B |
| Uniprot ID | Q9BXA7 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.45737483) |
| Ortholog in Animals | Dog_ TSSK1B ( ortholog_one2one ) Mouse_ Tssk1 ( ortholog_one2one ) Pig_ TSSK1B ( ortholog_one2one ) Rat_ Tssk1b ( ortholog_one2one ) Rabbit_ TSSK1B ( ortholog_one2one ) |
| Ohnologs | TSSK6, TSSK3 |
| Paralogs | TSSK6, SNRK, SIK2, SIK3, NIM1K, NUAK2, TSSK2, TSSK4, SIK1, PRKAA2, BRSK2, NUAK1, BRSK1, HUNK, PRKAA1, MELK, TSSK3 |
| Tissue | testis |
| Tissue Specificity | Testis-specific. Present in sperm (at protein level). {ECO:0000269|PubMed:15044604, ECO:0000269|PubMed:20729278}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs747955728 rs55930004 rs55940513 rs55738530 rs34696815 rs11953478 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000250}. Note=In spermatozoa, present in the sperm head and in the flagellum. {ECO:0000250}. |
| Mouse PG classification | NA |
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