| Gene Information | |
|---|---|
| Gene Name | UNQ6102/PRO20085 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1427 |
| Protein Names | A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q76LX8 |
| Gene Card | ADAMTS13 |
| Uniprot ID | Q76LX8 |
| Pfam | PF17771; PF19236; PF05986; PF01421; PF00090 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Plasma. Expressed primarily in liver. {ECO:0000269|PubMed:11574066}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3GHM (X-ray 2.60A ) 3GHN (X-ray 2.80A ) 3VN4 (X-ray 2.80A ) 6QIG (X-ray 2.80A ) 7B01 (X-ray 2.80A ) |
| DBSNP | rs34024143 rs281875297 rs281875302 rs121908467 rs121908469 rs281875291 rs281875289 rs281875287 rs121908470 rs281875298 rs281875292 rs281875304 rs281875337 rs121908478 rs281875293 rs121908477 rs281875285 rs281875336 rs149517360 rs281875294 rs281875288 rs281875338 rs281875306 rs121908471 rs2301612 rs36220239 rs36220240 rs11575933 rs281875296 rs281875305 rs281875286 rs121908473 rs281875299 rs281875290 rs28647808 rs36090624 rs281875335 rs281875295 rs281875307 rs121908475 rs41314453 rs36221451 rs281875300 rs685523 rs78977446 rs281875301 rs281875301 rs121908468 rs36222275 rs121908472 rs28503257 rs142572218 rs782383410 rs281875340 rs121908474 rs281875339 rs36222894 rs281875303 rs142060916 rs281875308 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12791682}. Note=Secretion enhanced by O-fucosylation of TSP type-1 repeats. |
| Mouse PG classification | NA |
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