| Gene Information | |
|---|---|
| Gene Name | TUBB4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain) |
| Target Name | tubulin beta-4b chain |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000188229 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P68371 |
| Gene Card | TUBB4B |
| Uniprot ID | P68371 |
| Pfam | PF00091; PF03953 |
| In ASD | no |
| Allosteric Prediction | yes (0.669325065) |
| Ortholog in Animals | Alpaca_ TUBB4B ( ortholog_one2one ) Dog_ TUBB4B ( ortholog_one2one ) GuineaPig_ TUBB4B ( ortholog_one2one ) Mouse_ Tubb4b ( ortholog_one2one ) Pig_ TUBB4B ( ortholog_one2one ) Rat_ Tubb4b ( ortholog_one2one ) |
| Ohnologs | TUBB4A, TUBB |
| Paralogs | TUBB, TUBA4B, TUBA8, TUBA4A, TUBB6, TUBB3, TUBAL3, TUBG2, TUBB8, TUBB8B, TUBE1, TUBB1, TUBB4A, TUBA1B, TUBA1A, TUBA1C, TUBA3E, TUBA3C, TUBA3D, TUBD1, TUBG1, TUBB2A, TUBB2B |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:20191564}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1554786802 rs1554786803 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. |
| Mouse PG classification | NA |
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