| Gene Information | |
|---|---|
| Gene Name | SLCO4A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 722 |
| Protein Names | Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) |
| Target Name | organic anion transporter e |
| Target Type | Literature-reported target |
| Gene Age | 680 ( ENSG00000101187 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96BD0 |
| Gene Card | SLCO4A1 |
| Uniprot ID | Q96BD0 |
| Pfam | PF07648; PF03137 |
| In ASD | no |
| Allosteric Prediction | no (-0.371472634) |
| Ortholog in Animals | Alpaca_ SLCO4A1 ( ortholog_one2one ) Dog_ SLCO4A1 ( ortholog_one2one ) GuineaPig_ SLCO4A1 ( ortholog_one2one ) Macaque_ SLCO4A1 ( ortholog_one2one ) Mouse_ Slco4a1 ( ortholog_one2one ) Pig_ SLCO4A1 ( ortholog_one2one ) Rat_ Slco4a1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLCO6A1, SLCO4C1, SLCO5A1, SLCO2B1, SLCO1B1, SLCO3A1, SLCO1B3, SLCO1C1, SLCO1A2, SLCO2A1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, with the exception of spleen and leukocytes. Expressed in placental trophoblasts (PubMed:10873595, PubMed:12409283). Expressed in pancreas, kidney, skeletal muscle, liver, lung, brain, heart, colon, small intestine, ovary, testis, prostate, thymus and spleen. Expressed in fetal brain, heart, kidney, liver, lung, skeletal muscle, spleen and pancreas (PubMed:10873595). {ECO:0000269|PubMed:10873595, ECO:0000269|PubMed:12409283}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34419428 rs1047099 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |