Gene Information
Gene NameHYAL4
OrganismHomo sapiens (Human)
Gene Length481
Protein NamesHyaluronidase-4 (Hyal-4) (EC 3.2.1.35) (Chondroitin sulfate endo-beta-N-acetylgalactosaminidase) (Chondroitin sulfate hydrolase) (CSHY) (Hyaluronoglucosaminidase-4)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000106302 )
Evolutionary StageEumetazoa
AlphaFoldDBQ2M3T9
Gene CardHYAL4
Uniprot IDQ2M3T9
PfamPF01630
In ASDno
Allosteric Predictionno (-0.584080096)
Ortholog in AnimalsAlpaca_ HYAL4 ( ortholog_one2one )
Dog_ HYAL4 ( ortholog_one2one )
GuineaPig_ HYAL4 ( ortholog_one2one )
Macaque_ HYAL4 ( ortholog_one2one )
Mouse_ Hyal4 ( ortholog_one2one )
Pig_ HYAL4 ( ortholog_one2one )
Rat_ Hyal4 ( ortholog_one2one )
Rabbit_ HYAL4 ( ortholog_one2one )
OhnologsHYAL2, HYAL1, HYAL3
ParalogsHYAL3, HYAL1, HYAL2, SPAM1
TissueNA
Tissue SpecificityDetected in placenta and skeletal muscle. {ECO:0000269|PubMed:10493834}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs6949082 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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