| Gene Information | |
|---|---|
| Gene Name | NLK |
| Organism | Homo sapiens (Human) |
| Gene Length | 527 |
| Protein Names | Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000087095 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBE8 |
| Gene Card | NLK |
| Uniprot ID | Q9UBE8 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.281398377) |
| Ortholog in Animals | Alpaca_ NLK ( ortholog_one2one ) Dog_ NLK ( ortholog_one2one ) GuineaPig_ NLK ( ortholog_one2one ) Macaque_ NLK ( ortholog_one2one ) Mouse_ Nlk ( ortholog_one2one ) Pig_ NLK ( ortholog_one2one ) Rat_ RGD1561440 ( ortholog_one2many ) Rat_ Tmem97 ( ortholog_one2many ) Rabbit_ NLK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAPK8, MAPK10, MAPK1, MAPK6, MAPK12, MAPK13, SRPK1, SRPK3, MAPK4, MAPK14, MAPK3, MOK, MAPK11, MAK, MAPK15, MAPK7, SRPK2, MAPK9, CILK1 |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001657(Rat);0.0125(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11871287 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Predominantly nuclear. A smaller fraction is cytoplasmic (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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