| Gene Information | |
|---|---|
| Gene Name | CENP-34 |
| Organism | Homo sapiens (Human) |
| Gene Length | 326 |
| Protein Names | Ras association domain-containing protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P50749 |
| Gene Card | RASSF2 |
| Uniprot ID | P50749 |
| Pfam | PF16517; PF00788 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. {ECO:0000269|PubMed:12732644}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.088150(Mouse);NULL(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs758816530 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}. Note=Translocates to the cytoplasm in the presence of STK3/MST2 and STK4/MST1. |
| Mouse PG classification | NA |
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