| Gene Information | |
|---|---|
| Gene Name | ZHX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 873 |
| Protein Names | Zinc fingers and homeoboxes protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000165156 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UKY1 |
| Gene Card | ZHX1 |
| Uniprot ID | Q9UKY1 |
| Pfam | PF00046; PF11569; PF18387 |
| In ASD | no |
| Allosteric Prediction | no (-0.465989063) |
| Ortholog in Animals | Alpaca_ ZHX1 ( ortholog_one2one ) Dog_ ZHX1 ( ortholog_one2one ) Macaque_ ZHX1 ( ortholog_one2one ) Mouse_ Zhx1 ( ortholog_one2one ) Pig_ ZHX1 ( ortholog_one2one ) Rat_ Zhx1 ( ortholog_one2one ) Rabbit_ ZHX1 ( ortholog_one2one ) |
| Ohnologs | ZHX3 |
| Paralogs | ZHX2, ZHX3, HOMEZ |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:10441475, ECO:0000269|PubMed:17056598}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ECB (NMR - ) 2GHF (NMR - ) 2LY9 (NMR - ) 3NAR (X-ray 2.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12237128, ECO:0000269|PubMed:17056598}. Note=Colocalized in the nucleus with DNMT3B. |
| Mouse PG classification | NA |
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