Gene Information
Gene NameHACS1
OrganismHomo sapiens (Human)
Gene Length373
Protein NamesSAM domain-containing protein SAMSN-1 (Hematopoietic adaptor containing SH3 and SAM domains 1) (Nash1) (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9NSI8
Gene CardSAMSN1
Uniprot IDQ9NSI8
PfamPF07647; PF07653; PF12485
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood. {ECO:0000269|PubMed:11594764, ECO:0000269|PubMed:15381729}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6UZJ  (NMR 
DBSNP rs34607574 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:11594764}. Cytoplasm {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity). {ECO:0000250}.
Mouse PG classificationNA
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