Gene Information
Gene NameGBP6
OrganismHomo sapiens (Human)
Gene Length633
Protein NamesGuanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)
Target NameNA
Target TypeNA
Gene Age55 ( ENSG00000183347 )
Evolutionary StageEukaryota
AlphaFoldDBQ6ZN66
Gene CardGBP6
Uniprot IDQ6ZN66
PfamPF02263; PF02841
In ASDno
Allosteric Predictionno (-0.362820782)
Ortholog in AnimalsAlpaca_ GBP6 ( ortholog_one2one )
Macaque_ GBP6 ( ortholog_one2one )
Mouse_ Gbp8 ( ortholog_one2many )
Mouse_ Gbp10 ( ortholog_one2many )
Mouse_ Gbp11 ( ortholog_one2many )
Mouse_ Gbp4 ( ortholog_one2many )
Mouse_ Gbp9 ( ortholog_one2many )
Mouse_ Gbp6 ( ortholog_one2many )
Rat_ Gbp6 ( ortholog_one2many )
OhnologsNA
ParalogsATL1, GBP5, ATL2, GBP7, ATL3, GBP2, GBP1, RNF112, GBP4, GBP3
Tissueesophagus, tongue, esophagus.mucosa
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs4582772  rs4658359  rs4658360  rs4658146  rs959460 
Subcellular location [CC]Cytoplasmic vesicle {ECO:0000250|UniProtKB:A0A0G2JDV3}.
Mouse PG classificationNA
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