| Gene Information | |
|---|---|
| Gene Name | GCNT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 428 |
| Protein Names | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2 beta-1,6-N-acetylglucosaminyltransferase) (C2GlcNAcT) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT) (Core 2 GNT) (Leukocyte type core 2 beta-1,6-N-acetylglucosaminyltransferase) (C2GnT-L) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000187210 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q02742 |
| Gene Card | GCNT1 |
| Uniprot ID | Q02742 |
| Pfam | PF02485 |
| In ASD | no |
| Allosteric Prediction | no (-0.955981447) |
| Ortholog in Animals | Alpaca_ GCNT1 ( ortholog_one2one ) Dog_ GCNT1 ( ortholog_one2one ) GuineaPig_ GCNT1 ( ortholog_one2one ) Macaque_ GCNT1 ( ortholog_one2one ) Mouse_ Gcnt1 ( ortholog_one2one ) Pig_ GCNT1 ( ortholog_one2one ) Rat_ Gcnt1 ( ortholog_one2one ) Rabbit_ GCNT1 ( ortholog_one2one ) |
| Ohnologs | GCNT3, GCNT4 |
| Paralogs | WSCD1, GCNT2, GCNT7, XYLT1, GCNT3, GCNT4, XYLT2, WSCD2 |
| Tissue | small.intestine |
| Tissue Specificity | Highly expressed in activated T-lymphocytes and myeloid cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2282683 rs11546569 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:23027862}; Single-pass type II membrane protein {ECO:0000269|PubMed:23027862}. Note=Also detected in the trans-Golgi network. |
| Mouse PG classification | NA |
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