Gene Information
Gene NameSEL1L
OrganismHomo sapiens (Human)
Gene Length794
Protein NamesProtein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000071537 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9UBV2
Gene CardSEL1L
Uniprot IDQ9UBV2
PfamPF00040; PF08238
In ASDno
Allosteric Predictionno (-0.648911614)
Ortholog in AnimalsAlpaca_ SEL1L ( ortholog_one2one )
Dog_ SEL1L ( ortholog_one2one )
GuineaPig_ SEL1L ( ortholog_one2one )
Macaque_ SEL1L ( ortholog_one2one )
Mouse_ Sel1l ( ortholog_one2one )
Pig_ SEL1L ( ortholog_one2one )
Rat_ Sel1l ( ortholog_one2one )
Rabbit_ SEL1L ( ortholog_one2one )
OhnologsSEL1L2
ParalogsSEL1L2, SEL1L3, LRP2BP, DELE1
TissueNA
Tissue SpecificityHighly expressed in pancreas.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.005155(Rat);0.071859(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11499034  rs1051193 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:16186509};
Single-pass type I membrane protein {ECO:0000269|PubMed:16186509}.
Mouse PG classificationNA
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