| Gene Information | |
|---|---|
| Gene Name | PPP3CB |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000107758 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P16298 |
| Gene Card | PPP3CB |
| Uniprot ID | P16298 |
| Pfam | PF00149 |
| In ASD | no |
| Allosteric Prediction | yes (0.425690458) |
| Ortholog in Animals | Alpaca_ PPP3CB ( ortholog_one2one ) Dog_ PPP3CB ( ortholog_one2one ) GuineaPig_ PPP3CB ( ortholog_one2one ) Macaque_ PPP3CB ( ortholog_one2one ) Mouse_ Ppp3cb ( ortholog_one2one ) Pig_ PPP3CB ( ortholog_one2one ) Rat_ Ppp3cb ( ortholog_one2many ) Rabbit_ PPP3CB ( ortholog_one2one ) |
| Ohnologs | PPP3CA |
| Paralogs | PPP6C, PPP5C, PPP2CB, PPP2CA, PPEF2, PPP4C, PPP3CA, PPEF1, PPP1CA, PPP1CC, PPP1CB, PPP3CC |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.099593(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4OR9 (X-ray 2.23A ) 4ORA (X-ray 2.75A ) 4ORC (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19154138}. |
| Mouse PG classification | NA |
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