| Gene Information | |
|---|---|
| Gene Name | UNQ301/PRO342 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6IA17 |
| Gene Card | SIGIRR |
| Uniprot ID | Q6IA17 |
| Pfam | PF01582 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in epithelial tissues such as kidney, lung and gut. {ECO:0000269|PubMed:14715412, ECO:0000269|PubMed:21077278}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs117739035 rs111819059 rs3210908 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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