| Gene Information | |
|---|---|
| Gene Name | DUTT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1651 |
| Protein Names | Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y6N7 |
| Gene Card | ROBO1 |
| Uniprot ID | Q9Y6N7 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with exception of kidney. {ECO:0000269|PubMed:9608531}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EO9 (NMR - ) 2V9Q (X-ray 2.50A ) 2V9R (X-ray 2.00A ) 2V9T (X-ray 1.70A ) 3WIH (X-ray 1.70A ) 4HLJ (X-ray 1.80A ) 5O5G (X-ray 3.03A ) 5O5I (X-ray 3.01A ) 5OPE (X-ray 2.54A ) 6A77 (X-ray 2.00A ) 6A78 (X-ray 2.10A ) 6A79 (X-ray 2.31A ) |
| DBSNP | rs9647397 rs919603543 rs35456279 rs36055689 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:24560577}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000250|UniProtKB:O89026}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:O55005}; Single-pass membrane protein {ECO:0000250|UniProtKB:O55005}. Note=Detected at growth cones in thalamus neurons. Detected at growth cones in thalamus neurons (By similarity). PRRG4 prevents cell surface location and both colocalize in the Endoplasmic reticulum/Golgi adjacent to the cell nucleus (By similarity). {ECO:0000250|UniProtKB:O55005, ECO:0000250|UniProtKB:O89026}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |