| Gene Information | |
|---|---|
| Gene Name | CYP3A5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 502 |
| Protein Names | Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3) |
| Target Name | cytochrome p450 3a subfamily |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000106258 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P20815 |
| Gene Card | CYP3A5 |
| Uniprot ID | P20815 |
| Pfam | PF00067 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000387579) |
| Ortholog in Animals | Alpaca_ CYP3A5 ( ortholog_one2one ) Dog_ CYP3A26 ( ortholog_many2many ) Dog_ CYP3A12 ( ortholog_many2many ) GuineaPig_ Cyp3a14 ( ortholog_many2many ) Mouse_ Cyp3a11 ( ortholog_many2many ) Mouse_ Cyp3a13 ( ortholog_many2many ) Mouse_ Cyp3a41b ( ortholog_many2many ) Mouse_ Cyp3a41a ( ortholog_many2many ) Mouse_ Cyp3a44 ( ortholog_many2many ) Mouse_ Cyp3a16 ( ortholog_many2many ) Mouse_ Cyp3a59 ( ortholog_many2many ) Mouse_ Cyp3a57 ( ortholog_many2many ) Mouse_ Cyp3a25 ( ortholog_many2many ) Rat_ AABR07035343.1 ( ortholog_many2many ) Rat_ Cyp3a9 ( ortholog_many2many ) Rat_ Cyp3a18 ( ortholog_many2many ) Rat_ AABR07035348.1 ( ortholog_many2many ) Rat_ Cyp3a23-3a1 ( ortholog_many2many ) Rat_ Cyp3a62 ( ortholog_many2many ) Rat_ AABR07035374.1 ( ortholog_many2many ) Rabbit_ CYP3A6 ( ortholog_one2many ) |
| Ohnologs | TBXAS1 |
| Paralogs | CYP3A4, CYP3A7, CYP3A43 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5VEU (X-ray 2.91A ) |
| DBSNP | rs55817950 rs28383468 rs56411402 rs28383477 rs28383479 rs28365092 rs28365083 rs41279854 rs28365085 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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