| Gene Information | |
|---|---|
| Gene Name | VANGL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Vang-like protein 1 (Loop-tail protein 2 homolog) (LPP2) (Strabismus 2) (Van Gogh-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000173218 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TAA9 |
| Gene Card | VANGL1 |
| Uniprot ID | Q8TAA9 |
| Pfam | PF06638 |
| In ASD | no |
| Allosteric Prediction | no (-1.029007977) |
| Ortholog in Animals | Alpaca_ VANGL1 ( ortholog_one2one ) Dog_ VANGL1 ( ortholog_one2one ) GuineaPig_ VANGL1 ( ortholog_one2one ) Macaque_ VANGL1 ( ortholog_one2one ) Mouse_ Vangl1 ( ortholog_one2one ) Pig_ VANGL1 ( ortholog_one2one ) Rat_ Vangl1 ( ortholog_one2one ) Rabbit_ VANGL1 ( ortholog_one2one ) |
| Ohnologs | VANGL2 |
| Paralogs | VANGL2 |
| Tissue | NA |
| Tissue Specificity | According to PubMed:11956595, ubiquitously expressed. According to PubMed:12011995, expressed specifically in testis and ovary. {ECO:0000269|PubMed:11956595, ECO:0000269|PubMed:12011995}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001578(Rat);0.31224(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61734296 rs146695372 rs4839469 rs201441696 rs761123443 rs121918218 rs201630629 rs121918219 rs145309218 rs121918220 rs34059106 rs775571796 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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