| Gene Information | |
|---|---|
| Gene Name | UNQ2531/PRO6030 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Transmembrane protein 25 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86YD3 |
| Gene Card | TMEM25 |
| Uniprot ID | Q86YD3 |
| Pfam | PF08205 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed within the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex. {ECO:0000269|PubMed:31424425}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35915434 rs12289253 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 4]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 2]: Secreted {ECO:0000305}.; [Isoform 3]: Secreted {ECO:0000305}.; Late endosome {ECO:0000250|UniProtKB:Q9DCF1}. Lysosome {ECO:0000250|UniProtKB:Q9DCF1}. |
| Mouse PG classification | NA |
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