Gene Information
Gene NameUNQ2427/PRO4987
OrganismHomo sapiens (Human)
Gene Length586
Protein NamesGuanylate-binding protein 5 (EC 3.6.5.-) (GBP-TA antigen) (GTP-binding protein 5) (GBP-5) (Guanine nucleotide-binding protein 5)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96PP8
Gene CardGBP5
Uniprot IDQ96PP8
PfamPF02263; PF02841
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in peripheral blood monocytes (at protein level). {ECO:0000269|PubMed:15175044}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7CKF  (X-ray  2.28A  7E59  (X-ray  3.00A  7E5A  (X-ray  2.50A 
DBSNP rs17130763  rs3806339 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:17266443, ECO:0000269|PubMed:21151871}. Golgi apparatus membrane {ECO:0000269|PubMed:17266443, ECO:0000269|PubMed:21151871};
Lipid-anchor {ECO:0000269|PubMed:21151871}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8CFB4}.
Mouse PG classificationNA
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