Gene Information
Gene NameUNQ237/PRO270
OrganismHomo sapiens (Human)
Gene Length296
Protein NamesThioredoxin-related transmembrane protein 2 (Cell proliferation-inducing gene 26 protein) (Thioredoxin domain-containing protein 14)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9Y320
Gene CardTMX2
Uniprot IDQ9Y320
PfamPF00085
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:12670024}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2DJ0  (NMR 
DBSNP rs145634348  rs1398376742  rs367990143  rs750470937  rs748116606  rs370455806  rs759161110 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:31735293};
Single-pass type I membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:31735293}. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria. {ECO:0000269|PubMed:31735293}.
Mouse PG classificationNA
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