| Gene Information | |
|---|---|
| Gene Name | UNQ337/PRO536 |
| Organism | Homo sapiens (Human) |
| Gene Length | 313 |
| Protein Names | Testis-expressed protein 264 (Putative secreted protein Zsig11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y6I9 |
| Gene Card | TEX264 |
| Uniprot ID | Q9Y6I9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7VED (X-ray 2.02A ) |
| DBSNP | rs11553574 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:31006537, ECO:0000269|PubMed:31006538}; Single-pass type III membrane protein {ECO:0000269|PubMed:31006537, ECO:0000269|PubMed:31006538}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:31006537, ECO:0000269|PubMed:31006538}. Cytoplasm, cytosol {ECO:0000269|PubMed:32152270}. Nucleus {ECO:0000269|PubMed:32152270}. Chromosome {ECO:0000269|PubMed:32152270}. Note=Is trafficked from tubular ER to growing autophagosomes via its cytosolic LIR motif (PubMed:31006537). Also found in the cytosol, nucleus and chromatin (PubMed:32152270). In response to formation of covalent DNA-protein cross-links (DPCs), localizes to the nuclear periphery, and associates with DNA replication forks (PubMed:32152270). {ECO:0000269|PubMed:31006537, ECO:0000269|PubMed:32152270}. |
| Mouse PG classification | NA |
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