| Gene Information | |
|---|---|
| Gene Name | EIF4A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) |
| Target Name | eukaryotic initiation factor 4a-i |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000161960 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P60842 |
| Gene Card | EIF4A1 |
| Uniprot ID | P60842 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | yes (0.55942267) |
| Ortholog in Animals | Alpaca_ EIF4A1 ( ortholog_one2one ) Dog_ EIF4A1 ( ortholog_one2one ) GuineaPig_ EIF4A1 ( ortholog_one2one ) Macaque_ EIF4A1 ( ortholog_one2one ) Mouse_ Eif4a1 ( ortholog_one2one ) Pig_ EIF4A1 ( ortholog_one2one ) Rat_ Eif4a1 ( ortholog_one2one ) |
| Ohnologs | EIF4A2 |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001920(Rat);0.017284(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2G9N (X-ray 2.25A ) 2ZU6 (X-ray 2.80A ) 3EIQ (X-ray 3.50A ) 5ZBZ (X-ray 1.31A ) 5ZC9 (X-ray 2.00A ) 6ZMW (EM 3.70A ) 7PPZ (X-ray 2.52A ) 7PQ0 (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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