| Gene Information | |
|---|---|
| Gene Name | TRIM36 |
| Organism | Homo sapiens (Human) |
| Gene Length | 728 |
| Protein Names | E3 ubiquitin-protein ligase TRIM36 (EC 2.3.2.27) (RING finger protein 98) (RING-type E3 ubiquitin transferase TRIM36) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152503 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NQ86 |
| Gene Card | TRIM36 |
| Uniprot ID | Q9NQ86 |
| Pfam | PF18568; PF00041; PF00643; PF13445 |
| In ASD | no |
| Allosteric Prediction | no (-0.831390975) |
| Ortholog in Animals | Alpaca_ TRIM36 ( ortholog_one2one ) Dog_ TRIM36 ( ortholog_one2one ) GuineaPig_ TRIM36 ( ortholog_one2one ) Macaque_ TRIM36 ( ortholog_one2one ) Mouse_ Trim36 ( ortholog_one2one ) Pig_ TRIM36 ( ortholog_one2one ) Rat_ Trim36 ( ortholog_one2one ) Rabbit_ TRIM36 ( ortholog_one2one ) |
| Ohnologs | MID2, MID1, FSD1, TRIM55, FSD2, TRIM46 |
| Paralogs | TRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM3, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM54, TRIM55, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in testis, prostate and brain (PubMed:15145053). Weakly expressed in kidney, lung and heart (PubMed:15145053). Expressed in fetal tissues (PubMed:28087737). {ECO:0000269|PubMed:15145053, ECO:0000269|PubMed:28087737}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs79290430 rs17137481 rs2974617 rs3749745 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:28087737}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q80WG7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q80WG7}. Note=Found in the acrosomal region of elongated spermatids and mature sperm. {ECO:0000250|UniProtKB:Q80WG7}. |
| Mouse PG classification | NA |
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