| Gene Information | |
|---|---|
| Gene Name | KIAA0153 |
| Organism | Homo sapiens (Human) |
| Gene Length | 644 |
| Protein Names | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14166 |
| Gene Card | TTLL12 |
| Uniprot ID | Q14166 |
| Pfam | PF03133 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the basal layer of prostate and endothelial cells. Increased expression in prostatic intraepithelial neoplasia and metastatic lesions. {ECO:0000269|PubMed:20162578}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.023983(Mouse);NULL(Rat);0.014815(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs138951 rs13058467 rs11704935 rs34074034 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20162578, ECO:0000269|PubMed:28011935}. Midbody {ECO:0000305|PubMed:20162578}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000305|PubMed:20162578}. Cytoplasm, cytoskeleton, spindle {ECO:0000305|PubMed:20162578}. Nucleus {ECO:0000269|PubMed:23251473}. Note=Predominantly localizes in the cytoplasm (PubMed:28011935). Partially colocalizes with vimentin in prostate cancer cells (PubMed:20162578). {ECO:0000269|PubMed:20162578, ECO:0000269|PubMed:28011935}. |
| Mouse PG classification | NA |
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