| Gene Information | |
|---|---|
| Gene Name | UNQ169/PRO195 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Transmembrane protein 59 (Liver membrane-bound protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BXS4 |
| Gene Card | TMEM59 |
| Uniprot ID | Q9BXS4 |
| Pfam | PF12280 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs41294776 |
| Subcellular location [CC] | Late endosome membrane {ECO:0000269|PubMed:23376921, ECO:0000269|PubMed:27273576}; Single-pass type I membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:23376921, ECO:0000269|PubMed:27273576}; Single-pass type I membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:23376921}; Single-pass type I membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:20427278}; Single-pass type I membrane protein {ECO:0000255}. Note=Mainly localizes to late endosomes/lysosomes. Probably first exported to the cell surface and then actively endocytosed to transiently localize in early endosomes on its way to the late endosomal/lysosomal compartment where it becomes quickly degraded. {ECO:0000269|PubMed:23376921}. |
| Mouse PG classification | NA |
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