| Gene Information | |
|---|---|
| Gene Name | RXFP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 374 |
| Protein Names | Relaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 12 ( ENSG00000173080 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TDU9 |
| Gene Card | RXFP4 |
| Uniprot ID | Q8TDU9 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.482025781) |
| Ortholog in Animals | Alpaca_ RXFP4 ( ortholog_one2one ) Mouse_ Rxfp4 ( ortholog_one2one ) Pig_ RXFP4 ( ortholog_one2one ) |
| Ohnologs | RXFP3 |
| Paralogs | BDKRB2, BDKRB1, GPR15, AGTR2, GPR25, APLNR, AGTR1 |
| Tissue | NA |
| Tissue Specificity | Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. {ECO:0000269|PubMed:14530218}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2152051 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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