| Gene Information | |
|---|---|
| Gene Name | UNC80 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3258 |
| Protein Names | Protein unc-80 homolog |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000144406 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | UNC80 |
| Uniprot ID | Q8N2C7 |
| Pfam | PF19424; PF20262; PF15778 |
| In ASD | no |
| Allosteric Prediction | no (-0.352183969) |
| Ortholog in Animals | Alpaca_ UNC80 ( ortholog_one2one ) Dog_ UNC80 ( ortholog_one2one ) GuineaPig_ UNC80 ( ortholog_one2one ) Macaque_ UNC80 ( ortholog_one2one ) Mouse_ Unc80 ( ortholog_one2one ) Pig_ UNC80 ( ortholog_one2one ) Rat_ Unc80 ( ortholog_one2one ) Rabbit_ UNC80 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | adrenal.gland, brain, testis, cerebellar.hemisphere, cerebellum, pituitary.gland |
| Tissue Specificity | Moderately expressed in fetal brain, spinal cord, skeletal muscle, thymus, spleen, fetal liver, small intestine, colon, kidney and uterus. Highly expressed in adrenal gland, prostate and testis, as well as in brain and cerebellum. {ECO:0000269|PubMed:26545877}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7SX3 (EM 3.10A ) 7SX4 (EM 3.50A ) 7WJI (EM 4.50A ) |
| DBSNP | rs35822936 rs864321623 rs4673492 rs869025316 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:32494638}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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