| Gene Information | |
|---|---|
| Gene Name | UNC50 |
| Organism | Homo sapiens (Human) |
| Gene Length | 259 |
| Protein Names | Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) (Protein GMH1 homolog) (hGMH1) (Uncoordinated-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000115446 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q53HI1 |
| Gene Card | UNC50 |
| Uniprot ID | Q53HI1 |
| Pfam | PF05216 |
| In ASD | no |
| Allosteric Prediction | no (-0.549291834) |
| Ortholog in Animals | Alpaca_ UNC50 ( ortholog_one2one ) Dog_ UNC50 ( ortholog_one2one ) GuineaPig_ UNC50 ( ortholog_one2one ) Macaque_ UNC50 ( ortholog_one2one ) Mouse_ Unc50 ( ortholog_one2one ) Pig_ UNC50 ( ortholog_one2one ) Rat_ Unc50 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Present in periodontal ligament fibroblasts (at protein level). {ECO:0000269|PubMed:17004066}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000250|UniProtKB:O55227}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O55227}. Golgi apparatus membrane {ECO:0000269|PubMed:12808035}; Multi-pass membrane protein {ECO:0000269|PubMed:12808035}. |
| Mouse PG classification | NA |
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