| Gene Information | |
|---|---|
| Gene Name | GRIN3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1043 |
| Protein Names | Glutamate receptor ionotropic, NMDA 3B (GluN3B) (N-methyl-D-aspartate receptor subtype 3B) (NMDAR3B) (NR3B) |
| Target Name | glutamate (nmda) receptor |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000116032 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60391 |
| Gene Card | GRIN3B |
| Uniprot ID | O60391 |
| Pfam | PF00060; PF10613 |
| In ASD | no |
| Allosteric Prediction | yes (1.054680108) |
| Ortholog in Animals | Alpaca_ GRIN3B ( ortholog_one2one ) Dog_ GRIN3B ( ortholog_one2one ) GuineaPig_ GRIN3B ( ortholog_one2one ) Macaque_ GRIN3B ( ortholog_one2one ) Mouse_ Grin3b ( ortholog_one2one ) Pig_ GRIN3B ( ortholog_one2one ) Rat_ Grin3b ( ortholog_one2one ) |
| Ohnologs | GRIN3A |
| Paralogs | GRIN3A, GRIN2A, GRIK5, GRIN2C, GRID1, GRID2, GRIK3, GRIN2D, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIK2, GRIA4, GRIN2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2240154 rs201484790 rs199717057 rs370645758 rs143106549 rs200777913 rs1043645806 rs144334537 rs935843296 rs4807399 rs2240157 rs1253903191 rs1599457596 rs375104717 rs2240158 rs769335041 rs139187576 rs540348423 rs60621387 rs778377243 rs138448790 rs2285906 rs750024778 rs200419950 rs769956227 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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