| Gene Information | |
|---|---|
| Gene Name | UNC119 |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Protein unc-119 homolog A (Retinal protein 4) (hRG4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000109103 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13432 |
| Gene Card | UNC119 |
| Uniprot ID | Q13432 |
| Pfam | PF05351 |
| In ASD | no |
| Allosteric Prediction | no (-0.410481009) |
| Ortholog in Animals | Alpaca_ UNC119 ( ortholog_one2one ) Dog_ UNC119 ( ortholog_one2one ) GuineaPig_ UNC119 ( ortholog_one2one ) Macaque_ UNC119 ( ortholog_one2one ) Mouse_ Unc119 ( ortholog_one2one ) Pig_ UNC119 ( ortholog_one2one ) Rat_ Unc119 ( ortholog_one2one ) Rabbit_ UNC119 ( ortholog_one2one ) |
| Ohnologs | UNC119B |
| Paralogs | UNC119B |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in retina, in photoreceptor synapses and inner segments. Expressed in a much lesser extent in several other tissues. {ECO:0000269|PubMed:9761287}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.011765(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3GQQ (X-ray 1.95A ) 3RBQ (X-ray 2.00A ) 4GOJ (X-ray 2.10A ) 4GOK (X-ray 2.60A ) 5L7K (X-ray 2.10A ) 6H6A (X-ray 2.00A ) |
| DBSNP | rs199714731 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23535298}. Note=Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells. {ECO:0000269|PubMed:23535298}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |