Gene Information
Gene NameTCAF1
OrganismHomo sapiens (Human)
Gene Length921
Protein NamesTRPM8 channel-associated factor 1 (TRP channel-associated factor 1)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000198420 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9Y4C2
Gene CardTCAF1
Uniprot IDQ9Y4C2
PfamPF17291; PF13402
In ASDno
Allosteric Predictionno (-0.604496894)
Ortholog in AnimalsAlpaca_ TCAF1 ( ortholog_one2one )
Dog_ TCAF1 ( ortholog_one2one )
GuineaPig_ TCAF1 ( ortholog_one2one )
Macaque_ TCAF1 ( ortholog_one2one )
Mouse_ Tcaf1 ( ortholog_one2one )
Pig_ TCAF1 ( ortholog_one2one )
Rat_ Tcaf1 ( ortholog_one2one )
Rabbit_ TCAF1 ( ortholog_one2one )
OhnologsNA
ParalogsTCAF2C, TCAF2
TissueNA
Tissue SpecificityIsoform 2 is expressed in the prostate and strongly expressed in cancerous prostate samples. {ECO:0000269|PubMed:25559186}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:25559186}. Note=Colocalizes with TRPM8 on the plasma membrane. {ECO:0000269|PubMed:25559186}.
Mouse PG classificationNA
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