| Gene Information | |
|---|---|
| Gene Name | GPBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 473 |
| Protein Names | Vasculin (GC-rich promoter-binding protein 1) (Vascular wall-linked protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000062194 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q86WP2 |
| Gene Card | GPBP1 |
| Uniprot ID | Q86WP2 |
| Pfam | PF15337 |
| In ASD | no |
| Allosteric Prediction | no (-1.431085166) |
| Ortholog in Animals | Alpaca_ GPBP1 ( ortholog_one2one ) Dog_ GPBP1 ( ortholog_one2one ) GuineaPig_ GPBP1 ( ortholog_one2one ) Macaque_ GPBP1 ( ortholog_one2one ) Mouse_ Gpbp1 ( ortholog_one2one ) Pig_ GPBP1 ( ortholog_one2one ) Rat_ Gpbp1 ( ortholog_one2one ) Rabbit_ GPBP1 ( ortholog_one2one ) |
| Ohnologs | GPBP1L1 |
| Paralogs | GPBP1L1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Some isoforms may be specifically expressed in veins and arteries (at protein level). Isoform 4 is widely expressed. Isoform 1, isoform 2 and isoform 3 may be specifically expressed in vascular smooth muscle cells. {ECO:0000269|PubMed:12842993, ECO:0000269|PubMed:14612417}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1862171 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14612417}. Cytoplasm {ECO:0000269|PubMed:12842993}. Note=According to PubMed:12842993, it localizes to the cytoplasm. {ECO:0000269|PubMed:12842993}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |