| Gene Information | |
|---|---|
| Gene Name | DNAJC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 504 |
| Protein Names | DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000102580 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13217 |
| Gene Card | DNAJC3 |
| Uniprot ID | Q13217 |
| Pfam | PF00226; PF09976; PF13181 |
| In ASD | no |
| Allosteric Prediction | yes (0.307854117) |
| Ortholog in Animals | Alpaca_ DNAJC3 ( ortholog_one2one ) Dog_ DNAJC3 ( ortholog_one2one ) GuineaPig_ DNAJC3 ( ortholog_one2one ) Macaque_ DNAJC3 ( ortholog_one2one ) Mouse_ Dnajc3 ( ortholog_one2one ) Pig_ DNAJC3 ( ortholog_one2one ) Rat_ Dnajc3 ( ortholog_one2one ) Rabbit_ DNAJC3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DNAJC10, DNAJC18, DNAJC2, DNAJC7, DNAJC12, DNAJC5, DNAJC16, DNAJC24, DNAJC9, DNAJC5G, DNAJC13, DNAJC5B, DNAJC4, DNAJC30, DNAJC11, DNAJC14, DNAJC1, DNAJC17, DNAJC21, DNAJC25 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels. {ECO:0000269|PubMed:8666242}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002419(Rat);0.025000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2Y4T (X-ray 3.00A ) 2Y4U (X-ray 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250}. |
| Mouse PG classification | LPG |
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