Gene Information
Gene NameULK4
OrganismHomo sapiens (Human)
Gene Length1275
Protein NamesSerine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000168038 )
Evolutionary StageEukaryota
AlphaFoldDBQ96C45
Gene CardULK4
Uniprot IDQ96C45
PfamPF00069
In ASDno
Allosteric Predictionno (-0.559297502)
Ortholog in AnimalsAlpaca_ ULK4 ( ortholog_one2one )
Dog_ ULK4 ( ortholog_one2one )
Macaque_ ULK4 ( ortholog_one2one )
Mouse_ Ulk4 ( ortholog_one2one )
Pig_ ULK4 ( ortholog_one2one )
Rat_ Ulk4 ( ortholog_one2one )
Rabbit_ ULK4 ( ortholog_one2one )
OhnologsNA
ParalogsSTK36
Tissuetestis
Tissue SpecificityExpressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level). {ECO:0000269|PubMed:24284070}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.2(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6TSZ  (X-ray  1.90A  6U5L  (X-ray  1.75A 
DBSNP rs34538622  rs2272007  rs35833603  rs55840267  rs1716975  rs35263917  rs371185820  rs75907560  rs1052501  rs3774372  rs17063572  rs4973986  rs17215589  rs12488691  rs6769117 
Subcellular location [CC]NA
Mouse PG classificationNA
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