| Gene Information | |
|---|---|
| Gene Name | ULK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1036 |
| Protein Names | Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) |
| Target Name | serine/threonine-protein kinase ulk2 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000083290 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IYT8 |
| Gene Card | ULK2 |
| Uniprot ID | Q8IYT8 |
| Pfam | PF12063; PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.064212078) |
| Ortholog in Animals | Alpaca_ ULK2 ( ortholog_one2one ) Dog_ ULK2 ( ortholog_one2one ) GuineaPig_ ULK2 ( ortholog_one2one ) Macaque_ ULK2 ( ortholog_one2one ) Mouse_ Ulk2 ( ortholog_one2one ) Pig_ ULK2 ( ortholog_one2one ) Rat_ Ulk2 ( ortholog_one2one ) Rabbit_ ULK2 ( ortholog_one2one ) |
| Ohnologs | ULK1 |
| Paralogs | ULK3, ULK1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6QAT (X-ray 2.77A ) 6QAU (X-ray 2.48A ) 6QAV (X-ray 2.05A ) 6YID (X-ray 2.70A ) |
| DBSNP | rs34670978 rs150122 rs4462660 rs55730189 rs35107651 |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000269|PubMed:18936157}; Peripheral membrane protein {ECO:0000269|PubMed:18936157}. Note=Localizes to pre-autophagosomal membrane. |
| Mouse PG classification | NA |
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