| Gene Information | |
|---|---|
| Gene Name | NKX3-2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 333 |
| Protein Names | Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000109705 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P78367 |
| Gene Card | NKX3-2 |
| Uniprot ID | P78367 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-1.179849028) |
| Ortholog in Animals | Alpaca_ NKX3-2 ( ortholog_one2one ) Dog_ NKX3-2 ( ortholog_one2one ) GuineaPig_ NKX3-2 ( ortholog_one2one ) Macaque_ NKX3-2 ( ortholog_one2one ) Mouse_ Nkx3-2 ( ortholog_one2one ) Pig_ NKX3-2 ( ortholog_one2one ) Rat_ Nkx3-2 ( ortholog_one2one ) Rabbit_ NKX3-2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NKX6-3, NKX2-8, NKX1-2, NKX2-1, NKX2-3, NKX2-2, NKX6-1, NKX1-1, NKX2-5, NKX6-2, NKX2-6, NKX2-4, NKX3-1 |
| Tissue | sigmoid.colon |
| Tissue Specificity | Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton. {ECO:0000269|PubMed:20004766}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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