| Gene Information | |
|---|---|
| Gene Name | UGT8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000174607 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q16880 |
| Gene Card | UGT8 |
| Uniprot ID | Q16880 |
| Pfam | PF00201 |
| In ASD | no |
| Allosteric Prediction | no (-0.285976122) |
| Ortholog in Animals | Alpaca_ UGT8 ( ortholog_one2one ) Dog_ UGT8 ( ortholog_one2one ) GuineaPig_ UGT8 ( ortholog_one2one ) Macaque_ UGT8 ( ortholog_one2one ) Mouse_ Ugt8a ( ortholog_one2one ) Pig_ UGT8 ( ortholog_one2one ) Rat_ Ugt8 ( ortholog_one2one ) Rabbit_ UGT8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UGT2B15, UGT2B17, UGT2A3, UGT3A1, UGT1A3, UGT1A4, UGT1A5, UGT2B4, UGT2B7, UGT3A2, UGT1A1, UGT1A10, UGT1A8, UGT1A7, UGT1A9, UGT2A1, UGT2A2, UGT1A6, UGT2B10, UGT2B11, UGT2B28 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4148254 rs11098261 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q09426}. |
| Mouse PG classification | NA |
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