| Gene Information | |
|---|---|
| Gene Name | F13A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 732 |
| Protein Names | Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) |
| Target Name | coagulation factor xiii a chain |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000124491 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P00488 |
| Gene Card | F13A1 |
| Uniprot ID | P00488 |
| Pfam | PF00927; PF01841; PF00868 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000224408) |
| Ortholog in Animals | Alpaca_ F13A1 ( ortholog_one2one ) Dog_ F13A1 ( ortholog_one2one ) GuineaPig_ F13A1 ( ortholog_one2one ) Macaque_ F13A1 ( ortholog_one2one ) Mouse_ F13a1 ( ortholog_one2one ) Pig_ F13A1 ( ortholog_one2one ) Rat_ F13a1 ( ortholog_one2one ) |
| Ohnologs | TGM1 |
| Paralogs | TGM1, TGM6, TGM4, EPB42, TGM2, TGM3, TGM5, TGM7 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1EVU (X-ray 2.01A ) 1EX0 (X-ray 2.00A ) 1F13 (X-ray 2.10A ) 1FIE (X-ray 2.50A ) 1GGT (X-ray 2.65A ) 1GGU (X-ray 2.10A ) 1GGY (X-ray 2.50A ) 1QRK (X-ray 2.50A ) 4KTY (X-ray 1.98A ) 5MHL (X-ray 2.40A ) 5MHM (X-ray 2.12A ) 5MHN (X-ray 2.48A ) 5MHO (X-ray 2.92A ) |
| DBSNP | rs5985 rs759324596 rs3024472 rs746272012 rs779361778 rs376147795 rs3024477 rs1396702202 rs367679357 rs5984 rs5982 rs5983 rs138754417 rs757172838 rs369187276 rs17852475 rs5987 rs5988 rs375129902 rs121913064 rs377484555 rs778206273 |
| Subcellular location [CC] | Cytoplasm. Secreted {ECO:0000269|PubMed:4405643}. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. |
| Mouse PG classification | HPG |
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