| Gene Information | |
|---|---|
| Gene Name | PACSIN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000165912 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UKS6 |
| Gene Card | PACSIN3 |
| Uniprot ID | Q9UKS6 |
| Pfam | PF00611; PF14604 |
| In ASD | no |
| Allosteric Prediction | yes (0.689165959) |
| Ortholog in Animals | Alpaca_ PACSIN3 ( ortholog_one2one ) Dog_ PACSIN3 ( ortholog_one2one ) GuineaPig_ PACSIN3 ( ortholog_one2one ) Macaque_ PACSIN3 ( ortholog_one2one ) Mouse_ Pacsin3 ( ortholog_one2one ) Pig_ PACSIN3 ( ortholog_one2one ) Rat_ Pacsin3 ( ortholog_one2one ) Rabbit_ PACSIN3 ( ortholog_one2one ) |
| Ohnologs | PACSIN2, PACSIN1 |
| Paralogs | PACSIN2, PACSIN1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney. {ECO:0000269|PubMed:11082044, ECO:0000269|PubMed:11179684}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.102222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7106654 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11179684}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Detected at the inner aspect of the plasma membrane in myotubes. {ECO:0000250}. |
| Mouse PG classification | NA |
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