| Gene Information | |
|---|---|
| Gene Name | UGT1A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 534 |
| Protein Names | UDP-glucuronosyltransferase 1A3 (UGT1A3) (EC 2.4.1.17) (UDP-glucuronosyltransferase 1-3) (UDPGT 1-3) (UGT1*3) (UGT1-03) (UGT1.3) (UDP-glucuronosyltransferase 1-C) (UGT-1C) (UGT1C) (UDP-glucuronosyltransferase 1A isoform 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P35503 |
| Gene Card | UGT1A3 |
| Uniprot ID | P35503 |
| Pfam | PF00201 |
| In ASD | yes |
| Allosteric Prediction | yes (0.807205897) |
| Ortholog in Animals | Alpaca_ UGT1A3 ( ortholog_one2one ) Mouse_ Ugt1a2 ( ortholog_many2many ) Mouse_ Ugt1a5 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | UGT2B15, UGT2B17, UGT2A3, UGT3A1, UGT8, UGT2B4, UGT2B7, UGT3A2, UGT1A1, UGT1A10, UGT1A8, UGT1A7, UGT1A9, UGT2A1, UGT2A2, UGT1A6, UGT2B10, UGT2B11, UGT2B28, UGT1A4, UGT1A5 |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Expressed in liver, kidney, colon, esophagus and small intestine. {ECO:0000269|PubMed:18004212}.; [Isoform 2]: Expressed in liver, kidney and colon. Not expressed in esophagus and small intestine. {ECO:0000269|PubMed:18004212}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28898617 rs3821242 rs45625338 rs6431625 rs45595237 rs28898618 rs28898619 rs13406898 rs61764030 rs45449995 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305|PubMed:17179145}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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