| Gene Information | |
|---|---|
| Gene Name | UGCG |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (Glycosylceramide synthase) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase) |
| Target Name | ceramide glucosyltransferase |
| Target Type | Successful target |
| Gene Age | 1488 ( ENSG00000148154 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16739 |
| Gene Card | UGCG |
| Uniprot ID | Q16739 |
| Pfam | PF13506 |
| In ASD | no |
| Allosteric Prediction | yes (1.058693188) |
| Ortholog in Animals | Alpaca_ UGCG ( ortholog_one2one ) Dog_ UGCG ( ortholog_one2one ) GuineaPig_ UGCG ( ortholog_one2one ) Macaque_ UGCG ( ortholog_one2one ) Mouse_ Ugcg ( ortholog_one2one ) Pig_ UGCG ( ortholog_one2one ) Rat_ Ugcg ( ortholog_one2one ) Rabbit_ UGCG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in all tissues examined. {ECO:0000269|PubMed:8643456}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:12873973}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9R0E0}. |
| Mouse PG classification | NA |
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