| Gene Information | |
|---|---|
| Gene Name | UFD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 307 |
| Protein Names | Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000070010 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92890 |
| Gene Card | UFD1 |
| Uniprot ID | Q92890 |
| Pfam | PF03152 |
| In ASD | no |
| Allosteric Prediction | no (-0.334277103) |
| Ortholog in Animals | Alpaca_ UFD1 ( ortholog_one2one ) Dog_ UFD1 ( ortholog_one2one ) GuineaPig_ UFD1 ( ortholog_one2one ) Macaque_ UFD1 ( ortholog_one2one ) Mouse_ Ufd1 ( ortholog_one2one ) Pig_ UFD1 ( ortholog_one2one ) Rat_ Ufd1 ( ortholog_one2one ) Rabbit_ UFD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.077207(Mouse);NULL(Rat);0.028210(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YUJ (NMR - ) 5B6C (X-ray 1.55A ) 5C1B (X-ray 3.08A ) |
| DBSNP | rs17744624 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q9ES53}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9ES53}. |
| Mouse PG classification | NA |
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