| Gene Information | |
|---|---|
| Gene Name | UBXN4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 508 |
| Protein Names | UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000144224 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92575 |
| Gene Card | UBXN4 |
| Uniprot ID | Q92575 |
| Pfam | PF00789 |
| In ASD | no |
| Allosteric Prediction | no (-1.083514001) |
| Ortholog in Animals | Alpaca_ UBXN4 ( ortholog_one2one ) Dog_ UBXN4 ( ortholog_one2one ) GuineaPig_ UBXN4 ( ortholog_one2one ) Macaque_ UBXN4 ( ortholog_one2one ) Mouse_ Ubxn4 ( ortholog_one2one ) Pig_ UBXN4 ( ortholog_one2one ) Rat_ Ubxn4 ( ortholog_one2one ) Rabbit_ UBXN4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBAC1, TNRC6C, UBXN1, TNRC6B, TNRC6A |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level). {ECO:0000269|PubMed:16968747}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KXJ (NMR - ) |
| DBSNP | rs2304602 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16968747}; Peripheral membrane protein {ECO:0000269|PubMed:16968747}. Nucleus envelope {ECO:0000269|PubMed:16968747}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER. {ECO:0000269|PubMed:16968747}. |
| Mouse PG classification | NA |
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