| Gene Information | |
|---|---|
| Gene Name | UBPY |
| Organism | Homo sapiens (Human) |
| Gene Length | 1118 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P40818 |
| Gene Card | USP8 |
| Uniprot ID | P40818 |
| Pfam | PF00581; PF00443; PF08969 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.492874(Rat);0.181980(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WHB (NMR - ) 2A9U (X-ray 2.10A ) 2GFO (X-ray 2.00A ) 2GWF (X-ray 2.30A ) 3N3K (X-ray 2.60A ) 6F09 (X-ray 1.59A ) |
| DBSNP | rs587777201 rs3743044 rs672601308 rs672601307 rs672601311 rs11638390 rs1056577 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16520378, ECO:0000269|PubMed:17711858, ECO:0000269|PubMed:19427866, ECO:0000269|PubMed:28505279}. Nucleus {ECO:0000250|UniProtKB:Q80U87}. Endosome membrane {ECO:0000269|PubMed:16520378, ECO:0000269|PubMed:17711858}; Peripheral membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:16520378}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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