| Gene Information | |
|---|---|
| Gene Name | UBE2W |
| Organism | Homo sapiens (Human) |
| Gene Length | 151 |
| Protein Names | Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000104343 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96B02 |
| Gene Card | UBE2W |
| Uniprot ID | Q96B02 |
| Pfam | PF00179 |
| In ASD | no |
| Allosteric Prediction | no (-0.873426354) |
| Ortholog in Animals | Alpaca_ UBE2W ( ortholog_one2one ) Dog_ UBE2W ( ortholog_one2one ) GuineaPig_ UBE2W ( ortholog_one2one ) Macaque_ UBE2W ( ortholog_one2one ) Mouse_ Ube2w ( ortholog_one2one ) Pig_ UBE2W ( ortholog_one2one ) Rat_ AABR07041109.1 ( ortholog_one2many ) Rat_ Ube2w ( ortholog_one2many ) Rabbit_ UBE2W ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBE2T, UBE2B, UBE2O, UBE2J2, UBE2A, UBE2C, UBE2H, UBE2V1, UBE2K, UBE2Z, UBE2F, UBE2G2, UBE2I, UBE2V2, UBE2N, UBE2NL, PEDS1, UBE2U, UBE2J1, UBE2G1, UBE2S, CDC34, UBE2R2, AKTIP |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in brain, liver, pancreas and heart. {ECO:0000269|PubMed:16368532}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2A7L (X-ray 1.82A ) 2MT6 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16368532, ECO:0000269|PubMed:21229326}. Note=In the nucleus, colocalizes with FANCL. {ECO:0000269|PubMed:21229326}. |
| Mouse PG classification | NA |
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